ACOX1 Antibody

Western Blot: ACOX1 Antibody [H00000051-A01] - Detection against Immunogen (98.71 KDa)

Product Discontinued

ACOX1 Antibody Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: ACOX1 (AAH10425, 1 a.a. - 660 a.a.) full-length recombinant protein with GST tag. MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHEDLNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKNFVHRGRPEPLDLHLGMFLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETIATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEMKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAEVHESYKHLKSLQSKL
• Specificity: ACOX1 - acyl-Coenzyme A oxidase 1, palmitoyl
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ACOX1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50 % glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ACOX1 Antibody

• ACOXEC 1.3.3.6
• acyl-CoA oxidase 1, palmitoyl
• acyl-CoA oxidase, straight-chain
• acyl-Coenzyme A oxidase 1, palmitoyl
• AOX
• PALMCOX
• Palmitoyl-CoA oxidase
• peroxisomal acyl-coenzyme A oxidase 1
• peroxisomal fatty acyl-CoA oxidase
• SCOXMGC1198
• Straight-chain acyl-CoA oxidase

Background

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ACOX1 Antibody (H00000051-A01)(3)

Publications using H00000051-A01

• Yu G, Cheng CJ, Lin SC et al. Organelle-Derived Acetyl-CoA Promotes Prostate Cancer Cell Survival, Migration, and Metastasis via Activation of Calmodulin Kinase II. Cancer Res 2018-05-15 [PMID: 29535221]
• Pelletier G, Rigden M, Poon R. Diesel and biodiesels induce hepatic palmitoyl-coa oxidase enzymatic activity through different molecular mechanisms in rats. J Biochem Mol Toxicol. 2012-05-14 [PMID: 22585588]
• Omi S, Nakata R, Okamura-Ikeda K et al. Contribution of Peroxisome-specific Isoform of Lon Protease in Sorting PTS1 Proteins to Peroxisomes. J Biochem;143(5):649-60. 2008-05-01 [PMID: 18281296]

Bioinformatics

• Gene Symbol: ACOX1
• Entrez:
  • 51(Human)
• OMIM:
  • 264470(Human)
• Uniprot:
  • AAH10425(Human)