ABCG5 Antibody (1B5D8)

Product Discontinued

ABCG5 Antibody (1B5D8) Summary

• Immunogen: Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ABCG5
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Flow Cytometry 1:200 - 1:400
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 72.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for ABCG5 Antibody (1B5D8)

• ATP-binding cassette sub-family G member 5
• ATP-binding cassette, sub-family G (WHITE), member 5
• ATP-binding cassette, subfamily G, member 5
• sterolin 1
• sterolin-1
• STSL

Background

The protein encoded by the ABCG5 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliaryexcretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene istandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene maycontribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.(provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABCG5