Applications: WB, ELISA, Flow, IHC, IHC-P, ICC/IF (-)
Host: Mouse Monoclonal
Species: Hu, Mu
Host: Rabbit Polyclonal
The protein encoded by the ABCG5 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into sevendistinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliaryexcretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene istandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene maycontribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.(provided by RefSeq)
|Product By Gene ID
- ATP-binding cassette sub-family G member 5
- sterolin 1
- ATP-binding cassette, subfamily G, member 5
- ATP-binding cassette, sub-family G (WHITE), member 5
Bioinformatics Tool for ABCG5
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