ABCG4 Antibody

• Reactivity: Hu, Mu, Rt, Ca
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ABCG4 Antibody Summary

• Description: Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-YLVLRYRVKSER corresponding to C-Terminus according to NP_071452.2.
• Epitope: C terminus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ABCG4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
• Application Notes: WB: Preliminary experiments in human brain (cerebellum, frontal cortex, hippocampus) and in mouse eye and rat retina lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ABCG4 Antibody

• ATP-binding cassette, sub-family G (WHITE), member 4
• ATP-binding cassette, subfamily G, member 4
• putative ABC transporter
• WHITE2ATP-binding cassette sub-family G member 4

Background

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ABCG4 Antibody (NBP1-20874)(1)

Publication using NBP1-20874

• Oldfield S, Lowry C, Ruddick J, Lightman S. ABCG4: a novel human white family ABC-transporter expressed in the brain and eye. Biochim Biophys Acta 2002-08-19 [PMID: 12183068]

Bioinformatics

• Gene Symbol: ABCG4
• Entrez:
  • 64137(Human)
  • 192663(Mouse)
  • 300664(Rat)
• Uniprot:
  • NP_071452.2(Human)