ABAT Antibody

Images

 
Western Blot: ABAT Antibody [NBP1-33066] - A. 30 ug SK-N-SH whole cell lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000.
Western Blot: ABAT Antibody [NBP1-33066] - Sample (50 ug of whole cell lysate) A: Mouse brain 7. 5% SDS PAGE; antibody diluted at 1:1000.
Western Blot: ABAT Antibody [NBP1-33066] - Hela cells
Western Blot: ABAT Antibody [NBP1-33066] - Rat liver lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.49 mg/ml

Order Details

ABAT Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human ABAT. The exact sequence is proprietary.
Localization
Mitochondrion matrix
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABAT
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.49 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ABAT Antibody

  • (S)-3-amino-2-methylpropionate transaminase
  • 4-aminobutyrate aminotransferase
  • 4-aminobutyrate aminotransferase, mitochondrial
  • 4-aminobutyrate transaminase
  • EC 2.6.1.19
  • EC 2.6.1.22
  • FLJ17813
  • FLJ30272
  • G
  • GABA aminotransferase
  • GABA transaminase
  • GABA transferase
  • GABA-AT
  • GABA-T
  • GABATNPD009
  • Gamma-amino-N-butyrate transaminase
  • hCG1984265
  • L-AIBAT

Background

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ABAT