5-HT1F Antibody - BSA Free

Immunohistochemistry-Paraffin: 5-HT1F Antibody [NLS3344] - Analysis of anti-5HT1F Receptor antibody with human kidney, renal tubules.

• Reactivity: Hu, Bt, Pm, Mu, Rt, Bv, Ca, Pm, Ha, Pm-Or, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

5-HT1F Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human 5-HT1F.
• Epitope: 3rd cytoplasmic domain
• Localization: Integral membrane protein
• Specificity: Human 5-HT1F. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TPRXL (47%).
• Predicted Species: Mouse (95%), Rat (95%), Hamster (95%), Canine (95%), Primate (100%), Bovine (95%), Orangutan (100%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HTR1F
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 6 - 9 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (95%), Equine (89%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for 5-HT1F Antibody - BSA Free

• 5HT1F
• 5-HT1F
• 5-HT-1F
• 5HT6
• 5-hydroxytryptamine (serotonin) receptor 1F
• HTR1EL
• HTR1ELMR77,5-HT1F5-hydroxytryptamine receptor 1F
• HTR1F
• MR77
• Serotonin receptor 1F

Background

5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HTR1F
• Entrez:
  • 3355(Human)