5-HT1F Antibody

Images

 
Immunohistochemistry-Paraffin: 5-HT1F Antibody [NLS3343] - Analysis of anti-HTR1F / 5-HT1F antibody with human brain, cortex, neurons at dilution 2-3 ug/ml.
Immunohistochemistry-Paraffin: 5-HT1F Antibody [NLS3343] - Analysis of anti-HTR1F / 5-HT1F antibody with liver.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bt, Bv, Ca, Ch, GP, Ha, Mk, Pm, Rb, Fi, Tr, XpSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

5-HT1F Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from C-terminus of human 5HT1F Receptor.
Specificity
Human 5HT1F Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1E (71%), HTR1D (59%), HTR1B (59%).
Predicted Species
Xenopus (94%), Turkey (100%), Fish (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HTR1F
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin assay dependent

Reactivity Notes

Chimpanzee, Gorilla, Orangutan, Gibbon. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Platypus (100%), Stickleback (94%), Pufferfish (94%), Opossum (88%), Lizard (88%), Equien (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for 5-HT1F Antibody

  • 5HT1F
  • 5-HT1F
  • 5-HT-1F
  • 5HT6
  • 5-hydroxytryptamine (serotonin) receptor 1F
  • HTR1EL
  • HTR1ELMR77,5-HT1F5-hydroxytryptamine receptor 1F
  • HTR1F
  • MR77
  • Serotonin receptor 1F

Background

5HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HTR1F
Entrez