Antibody suppliers

Adiponectin (also called ADIPOQ) is a cytokine expressed exclusively in adipose tissue. It has a number of functions, regulating lipid metabolism, gluconeogenesis and the inflammatory response. Adiponectin antibody products are widely used in diabetes, obesity and lipid metabolism research. Obesity and Type 2 Diabetes are linked to an increased risk of breast cancer in women.

The enzymes of the Matrix Metalloproteinase (MMP) family assist in the degradation of the extracellular matrix, under both normal and pathological conditions. MMP antibodies have identified roles in a number of physiological processes, such as embryonic development and tissue remodelling. They also regulate enzyme cascades, expression of various proteins and the migration of both normal and malignant cells.

The V5 tag antibody identifies the V5 epitope tag, enabling proteins of interest to be analyzed and studied via ELISA, Western blot and other immunochemical methods. We at Novus Biologicals are one of the leading suppliers of epitope tag reagents, with an extensive range of V5 tag antibody products on our antibody database.

Novus' Lightning-Link HRP Antibody Labeling Kit (cat# 701-0000) has received some glowing product reviews and customer feedback lately. One satisfied customer wrote, "Fast, efficient, stable direct HRP conjugation - best reagent we have found..." Another reviewer wrote, "This conjugation kit worked beautifully [and] the procedure is so simple. Although we had some [initial] concerns, it worked very well."

Novus is launching a new Travel Grant offer for researchers who provide feedback on our antibodies.

For each complete product review that you submit, you will be entered into a drawing for a $500 travel grant! We will select a winner every 3 months - giving you 4 chances for you to win each year!  The winner will receive a $200 airline voucher and $300 towards registration for a scientific conference of your choice.

Sorting Nexin Family Member 27 (SNX27) binds the cell membrane to regulate endocytic vesicular and protein trafficking. SNX27 has also been shown to play a key role in the endocytic recycling pathway, whereby internalized membrane proteins and lipids are degraded and recycled into the cell, in T lymphocytes. In their groundbreaking work on endocytic recycling pathways, Dr. F Maxfield and Dr. T McGraw showed that these pathways are essential for proper organelle maintenance and homeostatic regulation of molecules.

The MK167, or Ki67 antibody recognizes a nuclear protein encoded by the MK167 gene. Ki167 is involved with RNA transcription and essential to cellular proliferation, being expressed by proliferating cells at all stages of the active cell cycle; it is exclusively used as a marker for cellular proliferation.

Antibody suppliers, such as us at Novus Biologicals, supply a wide range of cell marker products, among them the Osteopontin antibody. Recently, the osteopontin antibody has proven useful in hepatic cancer research.

Osteopontin (OPN) is mainly expressed by the osteoblasts; its primary function is in the mineralization of bone. However, OPN is expressed to a lower degree in other areas of the body, being involved in cell adhesion, cell migration and the inflammatory response.

The caspases are a group of cysteine protease enzymes essential to apoptosis, inflammation and necrosis. Caspase 3 has been identified as one of the key mediators of apoptosis.

What is CD11b?

CD11b is an integrin family member which pairs with CD18 to form the CR3 heterodimer. CD11b is expressed on the surface of many leukocytes including monocytes, neutrophils, natural killer cells, granulocytes and macrophages, as well as on 8% of spleen cells and 44% of bone marrow cells. Functionally, CD11b regulates leukocyte adhesion and migration to mediate the inflammatory response.