Species: Hu
Applications: Flow, IHC, IP
Host: Rat Monoclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC/IF
Host: Mouse Monoclonal
Species: Mu, Ca(-)
Applications: WB, Flow, Func, IHC, IP, CyTOF-ready
Host: Rat Monoclonal
Species: Hu
Applications: WB
Description
CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
3689 |
| Alternate Names |
- 959 beta subunit precursor)10
- CD18 antigen
- CD18
- CD18beta 2
- cell surface adhesion glycoprotein (LFA-1
- CR3
- Integrin beta 2
- integrin beta-2
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- ITGB2
- LAD
- LCAMB
- leukocyte cell adhesion molecule CD18
- leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
- LFA-1 beta
- LFA-1
- MAC-1 beta
- MF17
- MFI7
- P150
- p150,95 beta
|
![Immunocytochemistry Integrin beta 2/CD18 Antibody (212701) [Unconjugated]](http://images.novusbio.com/fullsize2/Integrin_beta_2_MAB1730_Immunocytochemistry_10557.jpg)
![Flow Cytometry Integrin beta 2/CD18 Antibody (212701) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab1730_human-integrin-beta-2-cd18-mab-clone-212701-flow-cytometry-7220257555..jpg)
