Osteopontin/OPN Products

Description

Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine. Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the vitronectin receptor, which has specificity for osteopontin. Osteopontin is overexpressed in a variety of cancers, including lung, breast, colorectal, stomach, ovarian, melanoma and mesothelioma.

Bioinformatics

Entrez	6696 Human
Uniprot	NP_000573 Human
Product By Gene ID	6696
Alternate Names	BNSP Bone sialoprotein 1 Eta-1 MGC110940 Nephropontin OPN Osteopontin secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1) secreted phosphoprotein-1 (osteopontin, bone sialoprotein) Spp1 SPP-1 SPP1/CALPHA1 fusion Urinary stone protein Uropontin

Research Areas for Osteopontin/OPN

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Extracellular Matrix
Hypoxia

Related Osteopontin/OPN Blog Posts

Check out the latest blog posts on Osteopontin/OPN.

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