Novus Biologicals announces new phospho-MAP1B antibody

Novus recently launched a new phospho-MAP1B antibody (catalog # NBP1-42827), also known as SuperBUGS. This rabbit polyclonal is able to detect phosphorylated MAP1B at Thr1265.

MAP1B encodes for a phosphoprotein involved in microtubule development of growing axons and cones. MAP1B is phosphorylated at Ser1260 and Thr1265. MAP1B’s role in microtubule assembly makes it crucial to neurogenesis and the functionality of the nervous system. Disorders associated with this gene include a variety of neurological diseases, including giant axonal neuropathy and Fragile X syndrome.

Though Novus offers many MAP1B antibodies, NBP1-42827 is the only antibody that detects phosphorylated MAP1B. Antibodies directed to phosphorylated amino acids provide the advantage of determining whether proteins are phosphorylated by inducing agents, ultimately leading to genetic mutation and disease. Scales, et. al. conducted a study in 2009 using a panel of antibodies phospho-specific to MAP1B in order to identify kinases that phosphorylate MAP1B. They identified a dual-specific kinase that was proved through knockout studies to be involved in the regulation of microtubule stability (PMID: 19549690). View other recent publications referencing Novus’s new phospho-MAP1B antibody here.

This new phospho-MAP1B antibody is available in a 0.1 ml aliquot (catalog # NBP1-42827) and 25 ul sample size (catalog # NBP1-42827SS). This antibody cross-reacts with human, mouse, rat, and Xenopus and is useful for Immunofluorescence, Immunohistochemistry – Frozen, and Western Blot analysis. For more information, view the data sheet here.


For more information on this antibody or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via e-mail at


Release Date: 
Wednesday, June 23, 2010 - 06:00