New ApoE4 specific antibody from Novus Biologicals

New ApoE4 specific antibody from Novus Biologicals

Apolipoprotein E4 (ApoE4) is one of the three major isoforms of Apolipoprotein E (ApoE).  Antibodies are made to target each of the three major isoforms of ApoE, including ApoE2, ApoE3, and ApoE4.  Novus Biologicals announced a new antibody specific to ApoE4 this week.  This ApoE4-specific antibody (catalog # NBP1-49529) is useful for the study of coronary artery disease and Alzheimer's Disease.

Commercial ApoE4 antibodies made to this specific E4 isoform are rare.  Novus' new ApoE4 antibody is specific for Apo-E4 and does not cross-react with the Apo-E2 or Apo-E3 isoforms.  The ApoE4 antibody cross-reacts with human and is useful for ELISA, immunoprecipitation and Western blot analysis.  By Western blot, the Apo-E4 antibody recognizes a band at approximately 34kDa.

Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Individuals carrying the common ApoE4 variant are at higher risk of coronary artery disease. ApoE4 is the largest known genetic risk factor for late-onset Alzheimer's Disease.

Novus provides other apolipoprotein antibodies including ApoA1, ApoA4, ApoA5, ApoB, ApoJ and ApoM. For more information on this ApoE4 antibody or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via e-mail at

About Novus Biologicals (

Novus Biologicals is a biotechnology company whose mission is to accelerate scientific discovery by developing and marketing unique products in the forefront of science.  Novus Biologicals provides primary antibodies, secondary antibodies, conjugated antibodies, proteins, peptides, isotype and loading controls, RNAi, lysates, stem cell lines and antibody labeling kits to the bioscience community.  All of Novus' products are 100% guaranteed to work in the species and applications listed on the datasheet.  By serving niche and emerging markets, Novus Biologicals has formed and will continue to form ongoing partnerships with leading researchers.


Release Date: 
Wednesday, December 8, 2010 - 07:00