ApoE4 Antibody (4E4) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4E4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

ApoE4 Antibody (4E4) [DyLight 550] Summary

Immunogen
Synthetic peptide made to an internal region of human ApoE4 (within residues 100-150) [Uniprot: P02649]
Localization
Secreted
Specificity
This antibody is specific for ApoE4. It does not cross-react with the ApoE2 or ApoE3 isoforms.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
APOE
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ApoE4 Antibody (4E4) [DyLight 550]

  • Apo-E
  • apolipoprotein E
  • apolipoprotein E3
  • late onset)
  • MGC1571

Background

ApoE4 is one of the three major isoforms of ApoE (Apolipoprotein E). These three major isoforms (ApoE2, ApoE3, and ApoE4) correspond to three common ApoE alleles and are recognized according to their relative position after isoelectric focusing. Individuals carrying the common ApoE4 variant are at higher risk of coronary artery disease. ApoE4 is also the largest known genetic risk factor for late-onset Alzheimer's Disease (AD).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-49529AF350
Alexa Fluor 405 NBP1-49529AF405
Alexa Fluor 488 NBP1-49529AF488
Alexa Fluor 532 NBP1-49529AF532
Alexa Fluor 594 NBP1-49529AF594
Alexa Fluor 647 NBP1-49529AF647
Alexa Fluor 700 NBP1-49529AF700
Alexa Fluor 750 NBP1-49529AF750
Biotin NBP1-49529B
DyLight 350 NBP1-49529UV
DyLight 405 NBP1-49529V
DyLight 488 NBP1-49529G
DyLight 550 NBP1-49529R
DyLight 594 NBP1-49529DL594
DyLight 650 NBP1-49529C
DyLight 680 NBP1-49529FR
DyLight 755 NBP1-49529IR
FITC NBP1-49529F
HRP NBP1-49529H
Janelia Fluor 549 NBP1-49529JF549
Janelia Fluor 646 NBP1-49529JF646

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Bioinformatics Tool for ApoE4 Antibody (NBP1-49529R)

Discover related pathways, diseases and genes to ApoE4 Antibody (NBP1-49529R). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for ApoE4 Antibody (NBP1-49529R)

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Blogs on ApoE4.

The C99 fragment of amyloid precursor protein (APP)
Alzheimer’s Disease (AD) is a neurodegenerative disorder that is characterized by an abundance of the beta-amyloid peptide in the brain.  When AD was first discovered, it was determined that beta-amyloid was produced as a result of the prote...  Read full blog post.

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Bioinformatics

Gene Symbol APOE