ApoE4 Antibody (4E4) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4E4
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

ApoE4 Antibody (4E4) [HRP] Summary

Immunogen
Synthetic peptide made to an internal region of human ApoE4 (within residues 100-150) [UniProt# P02649]
Localization
Secreted
Specificity
This antibody is specific for ApoE4. It does not cross-react with the ApoE2 or ApoE3 isoforms.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
APOE
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
This ApoE4 antibody (4E4) is useful for ELISA, Immunoprecipitation, and Western blot where a band can been seen at approximately 34 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ApoE4 Antibody (4E4) [HRP]

  • Apo-E
  • apolipoprotein E
  • apolipoprotein E3
  • late onset)
  • MGC1571

Background

ApoE4 is one of the three major isoforms of ApoE (Apolipoprotein E). These three major isoforms (ApoE2, ApoE3, and ApoE4) correspond to three common ApoE alleles and are recognized according to their relative position after isoelectric focusing. Individuals carrying the common ApoE4 variant are at higher risk of coronary artery disease. ApoE4 is also the largest known genetic risk factor for late-onset Alzheimer's Disease (AD).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for ApoE4 Antibody (NBP1-49529H) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NBP1-49529B
DyLight 405 Labeled NBP1-49529V
DyLight 488 Labeled NBP1-49529G
DyLight 550 Labeled NBP1-49529R
DyLight 650 Labeled NBP1-49529C
FITC Labeled NBP1-49529F

Additional ApoE4 Products

ApoE4 NBP1-49529H

Bioinformatics Tool for ApoE4 Antibody (NBP1-49529H)

Discover related pathways, diseases and genes to ApoE4 Antibody (NBP1-49529H). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for ApoE4 Antibody (NBP1-49529H)

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Pathways for ApoE4 Antibody (NBP1-49529H)

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PTMs for ApoE4 Antibody (NBP1-49529H)

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Research Areas for ApoE4 Antibody (NBP1-49529H)

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Blogs on ApoE4.

The C99 fragment of amyloid precursor protein (APP)
Alzheimer’s Disease (AD) is a neurodegenerative disorder that is characterized by an abundance of the beta-amyloid peptide in the brain.  When AD was first discovered, it was determined that beta-amyloid was produced as a result of the prote...  Read full blog post.

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Bioinformatics

Gene Symbol APOE