Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified
Notes
Manufactured by SDIX's proprietary Genomic Antibody Technology. GAT FAQs.
Alternate Names for CDK2AP1 Antibody
CDK2-associated protein 1cyclin-dependent kinase 2-associated protein 1
CDKAP1
cyclin-dependent kinase 2 associated protein 1
Deleted in oral cancer 1
Deleted in oral cancer-1
doc-1
DOC1Putative oral cancer suppressor
DORC1
p12DOC-1
ST19
Background
The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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