Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu, Mu, Rt
Applications: ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CDK2AP1 is encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
8099 |
| Alternate Names |
- CDK2-associated protein 1cyclin-dependent kinase 2-associated protein 1
- CDKAP1
- cyclin-dependent kinase 2 associated protein 1
- Deleted in oral cancer 1
- Deleted in oral cancer-1
- DOC-1
- doc-1
- DOC1Putative oral cancer suppressor
- DORC1
- p12DOC-1
- ST19
|
Research Areas for CDK2AP1
Find related products by research area and learn more about each of the different research areas below.
Breast CancerCancer
