XRN2 Antibody (OTI5F4) [DyLight 680]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI5F4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 680

XRN2 Antibody (OTI5F4) [DyLight 680] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 677-779 of human XRN2(NP_036387) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: XRN2
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: >95%

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for XRN2 Antibody (OTI5F4) [DyLight 680]

• 5'-3' exoribonuclease 2
• Dhm1-like protein (mouse homolog)
• DHM1-like protein
• DHP protein
• EC 3.1.13
• EC 3.1.13.-

Background

XRN2 is a 5'-to-3' exoribonuclease involved in 3'-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3'-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3'-end processing machinery by p54nrb/PSF.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: XRN2