XPE/DDB2 Antibody [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 700

XPE/DDB2 Antibody [Alexa Fluor® 700] Summary

• Immunogen: E. coli-derived recombinant human XPE/DDB2
  Met1-Lys427
  Accession # Q92466
• Specificity: Detects human XPE/DDB2 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for XPE/DDB2 Antibody [Alexa Fluor® 700]

• damage-specific DNA binding protein 2 (48kD)
• damage-specific DNA binding protein 2, 48kDa
• Damage-specific DNA-binding protein 2
• DDB p48 subunit
• DDB2
• DDBB
• DNA damage-binding protein 2
• FLJ34321
• UV-damaged DNA-binding protein 2
• UV-DDB 2
• UV-DDB2
• xeroderma pigmentosum group E protein
• XP5
• XPE/DDB2

Background

Xeroderma Pigmentosum complementation group E (XPE) patients are defective in a heterodimer of damage-specific DNA-binding activity (DDB1/DDB2). DDB2 is a 48 kDa protein upregulated in cells exposed to ultraviolet light. XP patients exhibit hypersensitivity to ultraviolet light and have a heightened incidence of skin cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.