XPE/DDB2 Products

Description

DDB2, also known as DNA damage-binding protein 2, consists of five isoforms of sizes 47.9 kDa, 26.7 kDa, 17.4 kDa, 40.7 kDa, and 26.8 kDa and is involved in repairing DNA damaged by ultraviolet light. Current research is being conducted on disorders and diseases including immunodeficiency, hepatitis, multiple sclerosis, lung cancer, ovarian cancer, skin cancer, and autosomal recessive disease. The protein has been linked to DNA repair and protein stability pathways where it interacts with CUL4A, DDB1, COPS5, ABL1, and E2F1.

Bioinformatics

Entrez	1643 Human
Uniprot	AAH00093 Human NM_000107 Human NP_000098 Human NP_000098.1 Human Q92466 Human
Product By Gene ID	1643
Alternate Names	damage-specific DNA binding protein 2 (48kD) damage-specific DNA binding protein 2, 48kDa Damage-specific DNA-binding protein 2 DDB p48 subunit DDBB DDBb DNA damage-binding protein 2 FLJ34321 UV-damaged DNA-binding protein 2 UV-DDB 2 UV-DDB2 xeroderma pigmentosum group E protein

Research Areas for XPE/DDB2

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
Nucleotide Excision Repair