xCT Recombinant Protein



Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, PA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

xCT Recombinant Protein Summary

XCT (Human) GST-Tagged Recombinant Protein

Source: Wheat Germ (in vitro)

in vitro wheat germ expression system
Details of Functionality
This protein is not active and should not be used for experiments requiring activity.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.


  • Western Blot
  • Protein Array
Application Notes
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for xCT Recombinant Protein

  • Amino acid transport system xc-
  • Calcium channel blocker resistance protein CCBR1
  • CCBR1
  • cystine/glutamate transporter
  • Member 11 (Slc7a11)
  • SLC7A11
  • Solute carrier family 7 member 11
  • solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
  • xCTCCBR1


SLC7A11 is a member of a heteromeric Na(+)-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc(-), the anionic form of cystine is transported in exchange for glutamate.[supplied by OMIM]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for xCT Recombinant Protein (H00023657-P01) (0)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for xCT Recombinant Protein (H00023657-P01) (0)

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Bioinformatics Tool for xCT Recombinant Protein (H00023657-P01)

Discover related pathways, diseases and genes to xCT Recombinant Protein (H00023657-P01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for xCT Recombinant Protein (H00023657-P01)

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Pathways for xCT Recombinant Protein (H00023657-P01)

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PTMs for xCT Recombinant Protein (H00023657-P01)

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Research Areas for xCT Recombinant Protein (H00023657-P01)

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Blogs on xCT.

The effects of ethanol consumption on glutamate production and xCT
xCT is a sodium independent glutamate transporter that regulates the exchange of extracellular l-cystine and intracellular l-glutamate across the plasma membrane. This process is critical to glutathione production and protection from subsequent ox...  Read full blog post.

xCT: The Membrane's Gatekeeper
xCT is an obligate, electroneutral, membrane-bound anionic transporter responsible for regulating particular amino acid gradients via their transport through plasma membrane. The antiporter xCT superficially resembles an ion channel and preferentially...  Read full blog post.

xCT: Amino Acid Transport and Disorders of the Central Nervous System
xCT, encoded by the gene SLC7A11, is a member of the heterodimeric amino acid transporter family. Proteins within this family are linked to one another via a disulphide bond to form heterodimers consisting of one light subunit and one heavy subunit (1...  Read full blog post.

xCT: Friend or Foe?
There are two opposing sides to the controversial cysteine/glutamate antiporter. On one hand, it can be viewed a guardian of the cell, protecting it from the damaging oxidative stress that can cause cell death and even cancer. But, conversely, it has...  Read full blog post.

Glutathione and xCT: Chemoresistance in Tumor Cells
Glutathione, called GSH in its reduced form and GSSG or L(-)-Glutathione in its oxidized form, is an endogenous antioxidant found in most cells in the body. Glutathione's functions include detoxifying xenobiotics from the body, assisting in membrane t...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol SLC7A11

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