Vitronectin Antibody Pair [HRP]

Sandwich ELISA: Vitronectin Antibody Pair [HRP] [NBP2-79457]

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP
• Standard Curve Range: 28.13-1800 pg/ml (example only; lot dependent)
• Sensitivity: 28.13 pg/ml (example only; lot dependent)

Vitronectin Antibody Pair [HRP] Summary

• Description: Solid Phase sandwich ELISA for the quantitative determination of Human Vitronectin.
• Specificity: This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human Vitronectin.
• Standard Curve Range: 28.13-1800 pg/ml (example only; lot dependent)
• Sensitivity: 28.13 pg/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Sample Volume: 100 ul
• Gene: VTN

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Vitronectin Antibody Pair [HRP]

• Complement S-protein
• epibolin
• Serum Spreading Factor
• Serum-spreading factor
• Somatomedin B
• S-protein
• V75
• vitronectin (serum spreading factor, somatomedin B, complement S-protein)
• Vitronectin
• VN
• VNT
• VTN

Background

Vitronectin also called serum spreading factor or complement S-protein, is a member of the pexin family (1). Found in serum and in tissues, Vitronectin exist in two forms; as a single chain (75kDa) and as a clipped form composed of two chains (65kDa and 10kDa). Vitronectin promotes cell adhesion, spreading and migration through specific interactions with cellular integrins, and inhibits cytolysis by the complement C5b-9 complex (2-4). Vitronectin also interacts with several critical proteins that regulate thrombosis and fibrinolysis. Vitronectin is phosphorylated by PKA and CKII (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: VTN