VGF Antibody (619707) [DyLight 550]

• Reactivity: Hu, Mu
• Applications: IHC
• Clone: 619707
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

VGF Antibody (619707) [DyLight 550] Summary

• Immunogen: E. coli-derived recombinant human VGF
  Thr554-Pro615
  Accession # O15240
• Specificity: Detects human and mouse VGF in direct ELISAs.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Gene: VGF
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for VGF Antibody (619707) [DyLight 550]

• neuro-endocrine specific protein VGF
• neurosecretory protein VGF
• VGF nerve growth factor inducible
• VGF

Background

Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VGF