VG5Q Antibody (368011) [Alexa Fluor™ Plus 488]

• Reactivity: Mu
• Clone: 368011
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 488

VG5Q Antibody (368011) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects mouse VG5Q in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VG5Q Antibody (368011) [Alexa Fluor™ Plus 488]

• AGGF1
• Angiogenic factor VG5Q
• angiogenic factor with G patch and FHA domains 1
• FLJ10283hVG5Q
• GPATC7G patch domain-containing protein 7
• GPATCH7HUS84971
• HSU84971
• VG5Q
• VG5QVasculogenesis gene on 5q protein

Background

Angiogenic Factor VG5Q, also known as AGGF1, is a presumably secreted protein expressed by vascular endothelial cells. Mouse VG5Q cDNA encodes a 714 aa precursor with a coiled coil domain, a forkhead (FHA) domain, and RNA-association domains (G-patch, OCRE). VG5Q binds the angiogenic TNF superfamily ligand TWEAK, and promotes endothelial cell proliferation. Human VG5Q mutations are associated with Klippel-Trenaunay syndrome, a congenital vascular morphogenesis disorder. Mouse VG5Q shares 78% aa identity with human VG5Q.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.