VEGFR3/Flt-4 Antibody (MM0003-7G63) - Azide and BSA Free

Western Blot: VEGFR3/Flt-4 Antibody (MM0003-7G63) - Azide and BSA Free [NB110-60968] - Lysate of human placenta tissue with Mouse Monoclonal anti-Human VEGFR3

Immunohistochemistry-Paraffin: VEGF R3/Flt-4 Antibody (MM0003-7G63) [NB110-60968] - Formalin Fixed and Paraffin embedded human placenta tissue section (Proteinase K pretreatment is required).

Product Discontinued

VEGFR3/Flt-4 Antibody (MM0003-7G63) - Azide and BSA Free Summary

• Immunogen: Human VEGFR3/Flt-4 (N-terminal)
• Specificity: No cross-reactivity is shown with VEGFR1 or VEGFR2.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FLT4
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for VEGFR3/Flt-4 Antibody (MM0003-7G63) - Azide and BSA Free

• EC 2.7.10
• EC 2.7.10.1
• FLT4
• Flt-4
• fms-related tyrosine kinase 4
• LMPH1A
• PCLFLT41
• soluble VEGFR3 variant 1
• soluble VEGFR3 variant 2
• soluble VEGFR3 variant 3
• Tyrosine-protein kinase receptor FLT4
• vascular endothelial growth factor receptor 3
• VEGF R3
• VEGFR3
• VEGFR-3
• VEGFR3Fms-like tyrosine kinase 4

Background

Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine esidues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, and increase vascular permeability in both large and small vessels. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. VEGF Receptor 3 is one of the five receptor tyrosine kinases (RTKs) (VEGF Receptor 1/Flt1, VEGF Receptor 2/KDR/Flk1, VEGF Receptor 3/Flt4, tie1 and tek/tie2) whose expression is almost exclusively restricted to endothelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FLT4
• Entrez:
  • 2324(Human)
• Uniprot:
  • P35916()