VEGFR1/R2/R3 Antibody (89106, 49560, 54733) [Phycoerythrin]

• Reactivity: Hu
• Applications: Flow
• Clone: 89106, 49560, 54733
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Phycoerythrin

VEGFR1/R2/R3 Antibody (89106, 49560, 54733) [Phycoerythrin] Summary

• Description: Reagent Information
  Phycoerythrin-conjugated mouse monoclonal anti-human VEGF R1 (Flt-1): Contains 250 µL of ready to use PE-labeled antibody (sufficient for 25 tests) clone # 49560 (Catalog # FAB321P). Mouse IgG1 isotype.
  Phycoerythrin-conjugated mouse monoclonal anti-human VEGF R2 (KDR): Contains 250 µL of ready to use PE-labeled antibody (sufficient for 25 tests) clone # 89106 (Catalog # FAB357P). Mouse IgG1 isotype.
  Phycoerythrin-conjugated mouse monoclonal anti-human VEGF R3 (Flt-4): Contains 250 µL of ready to use PE-labeled antibody (sufficient for 25 tests) clone # 54733 (Catalog # FAB3492P). Mouse IgG1 isotype.
• Additional Information: 1 vial each of PE-conjugated anti-VEGF R1 (clone 49560), VEGF R2 (clone 89106), and VEGF R3 (clone 54733)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Applications/Dilutions

• Dilutions:
  • Flow Cytometry

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VEGFR1/R2/R3 Antibody (89106, 49560, 54733) [Phycoerythrin]

• FLT;FLT1;FLT-1;Receptor protein-tyrosine kinase;Vascular endothelial growth factor receptor 1;VEGFR1;VEGFR-1
• VEGFR1, VEGFR2, VEGFR3

Background

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VEGFR1/R2/R3 Antibody (FABSP3P)(2)

Publications using FABSP3P

• Guinn, S;Kinny-Köster, B;Tandurella, JA;Mitchell, JT;Sidiropoulos, DN;Loth, M;Lyman, MR;Pucsek, AB;Zabransky, DJ;Lee, JW;Kartalia, E;Ramani, M;Seppälä, TT;Cherry, C;Suri, R;Zlomke, H;Patel, J;He, J;Wolfgang, CL;Yu, J;Zheng, L;Ryan, DP;Ting, DT;Kimmelman, AC;Gupta, A;Danilova, L;Elisseeff, JH;Wood, LD;Stein-O'Brien, G;Kagohara, LT;Jaffee, EM;Burkhart, RA;Fertig, EJ;Zimmerman, JW; Transfer learning reveals cancer-associated fibroblasts are associated with epithelial-mesenchymal transition and inflammation in cancer cells in pancreatic ductal adenocarcinoma Cancer research 2024-04-08 [PMID: 38587552] (Flow Cytometry, Human)
• Donald O. Freytes, John D. O’Neill, Yi Duan-Arnold, Emily A. Wrona, Gordana Vunjak-Novakovic Natural Cardiac Extracellular Matrix Hydrogels for Cultivation of Human Stem Cell-Derived Cardiomyocytes Methods in Molecular Biology 2015-06-08 [PMID: 25070328]