Vasorin/SLIT-like 2 Antibody [Biotin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

Vasorin/SLIT-like 2 Antibody [Biotin] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Vasorin/SLIT‑like 2
• Specificity: Detects human Vasorin/SLIT‑like 2 in Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: VASN
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Vasorin/SLIT-like 2 Antibody [Biotin]

• Atia
• Protein slit-like 2
• SLIT like 2
• Slitl2
• slit-like 2 (Drosophila)
• slit-like 2
• VASN
• Vasorin

Background

Vasorin is a type I membrane protein that is predominantly expressed in vascular smooth muscle cells in a developmentally regulated pattern. Expression is down-regulated during vessel repair after arterial injury. Vasorin directly binds to transforming growth factor (TGF)-beta and attenuates TGF-beta signaling in vitro (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Vasorin/SLIT-like 2 Antibody (BAF2140)(2)

Publications using BAF2140

• Hui Ling Yeo, Tan‐Chi Fan, Ruey‐Jen Lin, Jyh‐Cherng Yu, Guo‐Shiou Liao, Eric Sheng‐Wen Chen et al. Sialylation of vasorin by ST3Gal1 facilitates TGF‐ beta 1‐mediated tumor angiogenesis and progression International Journal of Cancer 2019-04-15 [PMID: 30252131]
• Gunawardana CG, Kuk C, Smith CR Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer. J. Proteome Res., 2009-10-01;8(10):4705-13. 2009-10-01 [PMID: 19663500] (ELISA Development, Human)

Bioinformatics

• Gene Symbol: VASN