VAP-1/AOC3 Antibody (4B8)

Immunocytochemistry/Immunofluorescence: VAP-1/AOC3 Antibody (4B8) [H00008639-M06] - Analysis of monoclonal antibody to AOC3 on HeLa cell. Antibody concentration 10 ug/ml

Sandwich ELISA: VAP-1/AOC3 Antibody (4B8) [H00008639-M06] - Detection limit for recombinant GST tagged AOC3 is 0.3 ng/ml as a capture antibody.

Product Discontinued

VAP-1/AOC3 Antibody (4B8) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: AOC3 (NP_003725, 351 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSH
• Specificity: AOC3 - amine oxidase, copper containing 3 (vascular adhesion protein 1) (4B8)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: AOC3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Sandwich ELISA
• Application Notes: It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for VAP-1/AOC3 Antibody (4B8)

• amine oxidase, copper containing 3 (vascular adhesion protein 1)
• AOC3
• Copper amine oxidase
• EC 1.4.3
• HPAO
• HPAOSSAO
• Semicarbazide-sensitive amine oxidase
• SSAO
• VAP1
• VAP-1
• VAP1EC 1.4.3.21
• VAP-1membrane primary amine oxidase
• Vascular adhesion protein 1

Background

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VAP-1/AOC3 Antibody (H00008639-M06)(1)

Publication using H00008639-M06

• Danoy M, Shinohara M, Rizki-Safitri A et al. Alteration of pancreatic carcinoma and promyeloblastic cell adhesion in liver microvasculature by co-culture of hepatocytes, hepatic stellate cells and endothelial cells in a physiologically-relevant model. Integr Biol (Camb) 2017-03-21 [PMID: 28322389]

Bioinformatics

• Gene Symbol: AOC3
• Entrez:
  • 8639(Human)
• Uniprot:
  • NP_003725()