USP48 Antibody

Western Blot: USP48 Antibody [NB100-59838] - Detection of Human and Mouse USP48 on HeLa whole cell lysate using NB100-59838. USP48 was also immunoprecipitated by another rabbit anti-USP48 antibody.

• Reactivity: Hu, Mu, Rt, Ch
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

USP48 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 985 and 1035 of human ubiquitin specific peptidase 48 using the numbering given in entry NP_115612.4 (GeneID 84196).
• Predicted Species: Rat (100%), Chicken (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USP48
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for USP48 Antibody

• Deubiquitinating enzyme 48
• DKFZp762M1713
• EC 3.1.2.15
• EC 3.4.19.12
• FLJ11328
• FLJ20103
• FLJ23054
• FLJ23277
• MGC132556
• MGC14879
• RAP1GA1
• synUSP
• ubiquitin carboxyl-terminal hydrolase 48
• ubiquitin specific peptidase 48
• ubiquitin specific protease 31
• ubiquitin specific protease 48
• ubiquitin thioesterase 48
• Ubiquitin thiolesterase 48
• Ubiquitin-specific-processing protease 48
• USP31
• USP48

Background

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 48 (USP48) is a member of the C19 peptidase family involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. USP48 is involved in the activation of NF-kappa B via its interaction with RELA and TRAF2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: USP48
• Entrez:
  • 84196(Human)
  • 170707(Mouse)
• Uniprot:
  • NP_115612.4(Human)