USP48 Products

Description

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 48 (USP48) is a member of the C19 peptidase family involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. USP48 is involved in the activation of NF-kappa B via its interaction with RELA and TRAF2.

Bioinformatics

Entrez	84196 Human 170707 Mouse
Uniprot	NP_115612 Human NP_115612.4 Human Q86UV5-7 Human
Product By Gene ID	84196
Alternate Names	FLJ20103 EC 3.1.2.15 FLJ11328 EC 3.4.19.12 USP31 ubiquitin thioesterase 48 Ubiquitin-specific-processing protease 48 ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin thiolesterase 48 RAP1GA1 Deubiquitinating enzyme 48 MGC132556 ubiquitin specific protease 48 DKFZp762M1713 ubiquitin specific protease 31 FLJ23277 MGC14879 FLJ23054 ubiquitin specific peptidase 48

Diseases related to USP48

Discover more about diseases related to USP48.

Atherosclerosis
Malignant Neoplasms
Inflammation

Bioinformatics Tool for USP48

Discover related pathways, diseases and genes to USP48. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.