Ubiquilin 1 Antibody

Western Blot: Ubiquilin 1 Antibody [NB120-3341] - Analysis of ubiquilin on CHO cell extract.

• Reactivity: Hu, Mu, ChHa, Ha
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

Ubiquilin 1 Antibody Summary

• Description: Novus Biologicals Rabbit Ubiquilin 1 Antibody (NB120-3341) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic Peptide: A(2) E S A E S G G P P G A Q D S A A(18)
• Specificity: Ubiquilin 1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: UBQLN1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/ml
• Application Notes: WB: Detects an approx. 63 kDa protein representing Ubiquilin from CHO cell extract.

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 16945923).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS with 1 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Ubiquilin 1 Antibody

• DA41
• DA41FLJ90054
• DSK2
• hPLIC-1
• PLIC1
• PLIC-1
• PLIC-1UBQN
• Protein linking IAP with cytoskeleton 1
• Ubiquilin 1
• ubiquilin-1
• UBQLN1
• UBQN
• XDRP1

Background

Ubiquilin 1 encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Review for Ubiquilin 1 Antibody (NB120-3341) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Mouse.

reviewed by: Stephen Smith WB Mouse 09/29/2010

Summary

• Application: Western Blot
• Sample Tested: mouse cortical lysate, Sample Amount: 20ug
• Species: Mouse
• Lot: kk138754

Bioinformatics

• Gene Symbol: UBQLN1
• Entrez:
  • 56085(Mouse)