u-Plasminogen Activator/Urokinase Antibody (B032M)

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications ELISA
Clone
B032M
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
3.14 mg/ml

Order Details

u-Plasminogen Activator/Urokinase Antibody (B032M) Summary

Immunogen
Recombinant rat PAI-1
Specificity
Rat Plasminogen Activator Inhibitor 1 (PAI-1)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PLAU
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000

Reactivity Notes

Reacts with Rat.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50mM Sodium Phosphate (pH 6.6) and 0.15M NaCl
Preservative
No Preservative
Concentration
3.14 mg/ml
Purity
Protein A purified

Alternate Names for u-Plasminogen Activator/Urokinase Antibody (B032M)

  • ATF
  • EC 3.4.21
  • EC 3.4.21.73
  • plasminogen activator, urokinase
  • PLAU
  • uPA
  • u-PA
  • uPlasminogen Activator
  • u-Plasminogen Activator
  • urinary
  • Urokinase
  • urokinase-type plasminogen activator

Background

PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type palsminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for u-Plasminogen Activator/Urokinase Antibody (NB110-68102)

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Diseases for u-Plasminogen Activator/Urokinase Antibody (NB110-68102)

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Bioinformatics

Gene Symbol PLAU
Entrez