TXNDC3 Antibody

Product Discontinued

TXNDC3 Antibody Summary

• Immunogen: Peptide with sequence C-TEPQTDTEPNERSE corresponding to internal region according to NP_057700.3.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: NME8
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
• Application Notes: WB: Preliminary experiments in human testis lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for TXNDC3 Antibody

• CILD6Sptrx-2
• EC 2.1.1.31
• EC 2.5.1.6
• NM23-H8
• NME8thioredoxin domain-containing protein 3
• Spermatid-specific thioredoxin-2
• sperm-specific thioredoxin 2
• SPTRX2sptrx-2
• thioredoxin domain containing 3 (spermatozoa)

Background

TXNDC3 encodes a group II thioredoxin protein, composed of a thioredoxin domain and 3 NDP kinase domains, with testis-specific expression.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TXNDC3 Antibody (NBP1-37001)(1)

Publication using NBP1-37001

• Duriez B, Duquesnoy P, Escudier E et al. A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia. Proc Natl Acad Sci U S A 2007-02-27 [PMID: 17360648]

Bioinformatics

• Gene Symbol: NME8
• Entrez:
  • 51314(Human)
• Uniprot:
  • NP_057700.3(Human)