DNAH11 Antibody

Immunohistochemistry-Paraffin: DNAH11 Antibody [NBP1-49883] - Pre-immune serum used as control. This antibody was able to detect DNAH11 in the cilia of respiratory epithelium of the Rhesus Macaque. Image courtesy of customer.

• Reactivity: Hu, Mu, Bv, Ca, RM
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

DNAH11 Antibody Summary

• Description: Novus Biologicals Goat DNAH11 Antibody (NBP1-49883) is a polyclonal antibody validated for use in IHC and ELISA. Anti-DNAH11 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence NVDEICEFNLNQ corresponding to internal region according to NP_003768.2.
• Epitope: NVDEICEFNLNQ - internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DNAH11
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
  • Peptide ELISA detection limit 1:32000
• Application Notes: WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as large as the calculated size of 521 kDa band according to NP_003768.2. IHC-P reactivity per customer review.

Reactivity Notes

Rhesus Macaque reactivity per customer review.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for DNAH11 Antibody

• Axonemal beta dynein heavy chain 11
• axonemal
• CILD7Dnahc11
• Ciliary dynein heavy chain 11
• DNAHBLFLJ30095
• DNAHC11FLJ37699
• DNHBL
• dynein, axonemal, heavy chain 11
• dynein, axonemal, heavy polypeptide 11
• dynein, ciliary, heavy chain 11

Background

The DNAH11 gene encodes a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DNAH11 Antibody (NBP1-49883)(1)

Publication using NBP1-49883

• Escudier E, Duquesnoy P, Papon JF, Amselem S. Ciliary defects and genetics of primary ciliary dyskinesia. Paediatr Respir Rev 2009-06-01 [PMID: 19410201]

Review for DNAH11 Antibody (NBP1-49883) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Rhesus Macaque.

reviewed by: Daniel Dugger IHC-P Rhesus Macaque 03/11/2017

Summary

• Application: Immunohistochemistry-Paraffin
• Sample Tested: Parafffin embedded lung tissue
• Species: Rhesus Macaque

Bioinformatics

• Gene Symbol: DNAH11
• Entrez:
  • 8701(Human)
  • 13411(Mouse)
• Uniprot:
  • NP_003768.2(Human)