TWEAK/TNFSF12 Overexpression Lysate (Denatured) Summary
Plasmid: pCMV-TNFSF12 full-length
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).
Lysate Details for TWEAK/TNFSF12
Quality control test: Transient overexpression cell lysate was tested with Anti-TNFSF12 antibody by Western Blots.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TWEAK/TNFSF12 Overexpression Lysate (Denatured)
- APO3 ligand
- DR3LGTWEAKAPO3/DR3 ligand
- TNF-related weak inducer of apoptosis
- tumor necrosis factor (ligand) superfamily, member 12
- tumor necrosis factor ligand superfamily member 12
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed
for 6 months from date of receipt.
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