TWEAK/TNFSF12 Overexpression Lysate (Denatured) Summary
tumor necrosis factor (ligand) superfamily, member 12
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
50mM Tris-HCl, 2%SDS, 10% glycerol, 2% 2-mercaptoethanol, pH 6.8.
The exact concentration of the protein of interest cannot be determined for overexpression lysates. Please contact technical support for more information.
This transient overexpression cell lysate is useful for western blot and was tested with Anti-TNFSF12 antibody H00008742-B01 by Western Blots.
Lysate Details for TWEAK/TNFSF12
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for TWEAK/TNFSF12 Overexpression Lysate (Denatured)
- APO3 ligand
- DR3LGTWEAKAPO3/DR3 ligand
- TNF-related weak inducer of apoptosis
- tumor necrosis factor (ligand) superfamily, member 12
- tumor necrosis factor ligand superfamily member 12
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed
for 6 months from date of receipt.
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