Human TWEAK/TNFSF12 ELISA Kit (Colorimetric)

ELISA: Human TWEAK/TNFSF12 ELISA Kit (Colorimetric) [NBP3-06808] - Samples were spiked with high concentrations of Human TWEAK/TNFSF12 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human TWEAK/TNFSF12 ELISA Kit (Colorimetric) [NBP3-06808] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, cell supernatant, and other biological fluids
• Standard Curve Range: 7.81 - 500 pg/mL
• Sensitivity: 4.69 pg/mL

Human TWEAK/TNFSF12 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human TWEAK/TNFSF12 in samples. No significant cross-reactivity or interference between Human TWEAK/TNFSF12 and analogues was observed.
• Standard Curve Range: 7.81 - 500 pg/mL
• Sensitivity: 4.69 pg/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: 5.22
• Intra-Assay: 5.07
• Spike Recovery: 87 - 110 %
• Sample Volume: 100 ul
• Kit Type: ELISA Kit (Colorimetric)
• Gene: TNFSF12

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human TWEAK/TNFSF12 ELISA Kit (Colorimetric)

• APO3 ligand
• APO3LMGC20669
• DR3LGTWEAKAPO3/DR3 ligand
• MGC129581
• TNF-related weak inducer of apoptosis
• TNFSF12
• tumor necrosis factor (ligand) superfamily, member 12
• tumor necrosis factor ligand superfamily member 12
• TWEAK

Background

CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia. ITEM-4 antibody reacts with both mouse and human Fn14. It is useful for flow cytometric analysis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: TNFSF12