TWA1 Antibody

Images

 
Western Blot: TWA1 Antibody [NBP1-77366] - TWA1 Antibody Human brain tissue lysate with C20orf11 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: TWA1 Antibody [NBP1-77366] - Immunofluorescence of TWA1 in rat brain tissue with TWA1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TWA1 Antibody [NBP1-77366] - TWA1 Antibody Rat brain tissue with C20orf11 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TWA1 Antibody Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TWA1. The immunogen is located within the last 50 amino acids of TWA1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GID8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
TWA1 Peptide (NBP1-77366PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TWA1 Antibody

  • bA305P22.1
  • C20orf11
  • chromosome 20 open reading frame 11
  • FLJ20602
  • GID complex subunit 8 homolog (S. cerevisiae)
  • Twa1
  • TWA1protein C20orf11
  • two hybrid associated protein 1
  • Two hybrid-associated protein 1 with RanBPM

Background

TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GID8
Uniprot