TSSC3 Antibody

Images

 
Immunohistochemistry-Paraffin: TSSC3 Antibody [NB100-1347] - NB100-1347 3.8ug/ml staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

TSSC3 Antibody Summary

Immunogen
Peptide with sequence C-EPSRPSPQPKPRTP corresponding to C-Terminus according to NP_003302.1.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
PHLDA2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 3 - 6 ug/ml
  • Immunohistochemistry-Paraffin 3 - 6 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Preliminary experiments gave no signal but low background in Jurkat and human placenta extracts at up to 1 ug/ml. IHC-P: placenta shows staining of the syncytiotrophoblasts.
Positive Control
Jurkat Lysate (NB800-PC2)
TSSC3 Lysate (NBL1-14368)
Placenta Lysate (NB820-59248)
Publications
Read Publication using NB100-1347.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TSSC3 Antibody

  • Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein
  • BWR1Cp17-Beckwith-Wiedemann region 1 C
  • HLDA2BRW1C
  • Imprinted in placenta and liver protein
  • IPLp17-BWR1C
  • pleckstrin homology-like domain family A member 2
  • pleckstrin homology-like domain, family A, member 2
  • TSSC3p17-Beckwith-Wiedemann region 1C
  • tumor suppressing subchromosomal transferable fragment cDNA 3
  • tumor suppressing subtransferable candidate 3
  • Tumor-suppressing STF cDNA 3 protein
  • Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein
  • tumor-supressing STF cDNA 3

Background

GenBank Accession Number - NP_003302. TSSC3 in encoded in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TSSC3 Antibody (NB100-1347)(1)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PHLDA2
Entrez
Uniprot