TRPM8 Antibody

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Western Blot: TRPM8 Antibody [NBP1-33165] - Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE, antibody diluted at 1:500.

Product Details

Summary
Reactivity Hu, Mu, Bv, Ca, GPSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.56 mg/ml

Order Details

TRPM8 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Trp-p8. The exact sequence is proprietary.
Localization
Membrane, Multi-pass membrane protein
Predicted Species
Mouse (90%), Bovine (95%), Guinea Pig (91%), Canine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPM8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
128 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rat (89%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.56 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRPM8 Antibody

  • CMR1
  • Long transient receptor potential channel 6
  • LTRPC6
  • LTrpC-6
  • MGC2849
  • short form of the TRPM8 cationic channel
  • transient receptor potential cation channel, subfamily M, member 8
  • Transient receptor potential p8
  • transient receptor potential subfamily M member 8
  • TRPM8
  • TRPP8
  • trp-p8
  • TRPP8transient receptor potential cation channel subfamily M member 8

Background

A novel gene, trp-p8 has an expression pattern within normal human tissues that is mostly restricted to prostate epithelial cells. Trp-p8 mRNA expression is at moderate levels in normal prostate tissue and appears to be elevated in prostate cancer. Notably, trp-p8 mRNA was also expressed in a number of nonprostatic primary tumors of the breast, colon, lung and skin origin, whereas transcripts encoding trp-p8 were hardly detected or not detected in the corresponding normal human tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TRPM8 Antibody (NBP1-33165)

Discover related pathways, diseases and genes to TRPM8 Antibody (NBP1-33165). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on TRPM8.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

TRPM8: The Multi-functional Ion Channel
TRPM8 is a transmembrane homo-tetramer ion channel that is activated by cold temperatures, cooling agents, and menthol stimuli. It belongs to a subgroup within the larger family of TRP cation channels (including the TRPV1 capsaicin receptor) that are...  Read full blog post.

Touch Infographic: From Touch Receptors to the Brain
The body contains thousands of receptors and nerves which allow us to experience the sense of touch, also referred to as tactile perception. The somatosensory system allows organisms to perceive and decode a wide range of tactile stimuli to allow for...  Read full blog post.

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Bioinformatics

Gene Symbol TRPM8
Entrez