TRPA1 Peptide

• Reactivity: Hu
• Concentration: 1 mg/ml

TRPA1 Peptide Summary

• Description: A peptide to TRPA1.
• Specificity: This peptide is specific for NB110-40763 only.
• Protein/Peptide Type: Peptide
• Gene: TRPA1

Applications/Dilutions

• Application Notes: This peptide is useful as a blocking peptide for NB110-40763. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Peptide dissolved in dH2O. Contains no BSA.
• Preservative: No Preservative
• Concentration: 1 mg/ml

Alternate Names for TRPA1 Peptide

• ANKTM1
• ANKTM1ankyrin-like with transmembrane domains 1
• Ankyrin-like with transmembrane domains protein 1
• Transformation-sensitive protein p120
• transient receptor potential cation channel subfamily A member 1
• transient receptor potential cation channel, subfamily A, member 1
• TRPA1
• Wasabi receptor

Background

Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. It is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: TRPA1