TRIF/TICAM1 Antibody Blocking Peptide

Product Discontinued

TRIF/TICAM1 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 14 amino acids near the carboxy terminus of human TRIF.

  Source: Synthetic

  (Accession #: NP_891549)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: TICAM1
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77221. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for TRIF/TICAM1 Antibody Blocking Peptide

• MGC35334
• Proline-rich, vinculin and TIR domain-containing protein B
• PRVTIRBTIR domain-containing adapter protein inducing IFN-beta
• Putative NF-kappa-B-activating protein 502H
• TICAM1
• TICAM-1TIR domain containing adaptor inducing interferon-beta
• TIR domain-containing adapter molecule 1
• TIR domain-containing adaptor molecule 1
• toll-like receptor adaptor molecule 1
• TRIF
• TRIFToll-interleukin-1 receptor domain-containing adapter protein inducinginterferon beta

Background

TICAM (Toll-interleukin 1 receptor domain (TIR)-containing adaptor molecule-1) or TRIF (Toll/IL-1 receptor domain-containing adapter inducing IFN-beta) plays an essential role in the MyD88-independent signaling of TLR3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

FAQs for TRIF/TICAM1 Protein (NBP1-77221PEP). (Showing 1 - 3 of 3 FAQ).

1. Can NBP1-77221PEP be used as a TRIF inhibitor?
   • NBP1-77221PEP is a blocking peptide specific to our TRIF antibody, NBP1-77221. This peptide corresponds to a 14 amino acid length near the C-terminus of the protein. We have never tested this as a TRIF inhibitor and can only guarantee it to perform in a blocking/competition assay to block the binding of that specific TRIF antibody.
2. We just purchased the TRIF inhibitor NBP1-77221PEP and we were wondering the EC50 to calculate which concentration of the peptides to use for our functional assays.
   • For our product NBP1-77221PEP, this item has unfortunately not been tested for functional assays and does not have a recorded EC50 value. This item is intended as the blocking peptide for NBP1-77221.
3. Could you tell me the ED50 of this item?
   • Our peptide NBP1-77221PEP is provided as the blocking peptide for the antibody NBP1-77221. It has not yet been tested for use in blocking with live cells or tissues and the ED50 has not been calculated for this peptide. 

Bioinformatics

• Gene Symbol: TICAM1