TREML2/TLT-2 Antibody (656906) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
656906
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 750
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

TREML2/TLT-2 Antibody (656906) [Alexa Fluor® 750] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse TREML2/TLT-2
His25-Ala270
Accession # Q2LA85
Specificity
Detects mouse TREML2/TLT-2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) TREM-1, -2, -2b, -3, -4, rmTREML1/TLT-1, rmTREML4/TLT-4, or recombinant human (rh) NKp44 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
TREML2
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TREML2/TLT-2 Antibody (656906) [Alexa Fluor® 750]

  • C6orf76
  • dJ238O23.1
  • FLJ13693
  • MGC149715
  • MGC149716
  • TLT2
  • TLT-2
  • TREML2
  • trem-like transcript 2 protein
  • triggering receptor expressed on myeloid cells-like 2
  • triggering receptor expressed on myeloid cells-like protein 2
  • UNQ6268/PRO20473

Background

TREML2, also called TLT-2 (Trem-like transcript 2) is a 33 kDa (predicted) type I transmembrane cell surface receptor and member of the Trem family of receptor proteins. Mouse TLT-2 is synthesized as a 329 amino acid (aa) precursor that contains a 24 aa signal sequence, a 246 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 38 aa cytoplasmic tail. Within the ECD are an Ig-like V-type domain (aa 25-126) and one potential site for N-linked glycosylation. Mature mouse TLT-2 shares 49% aa sequence identity with mature human TLT-2. Cell surface expression of TLT-2 is seen for most of the B and myeloid cell lines.  TLT-2 is also expressed constitutively on CD8+ T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TREML2
Entrez
Uniprot