TREML1/TLT-1 Antibody [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB, Flow, CyTOF-ready
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 594

TREML1/TLT-1 Antibody [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human TREML1/TLT‑1
  Gln16-Ser160
  Accession # Q86YW5
• Specificity: Detects human TREML1/TLT‑1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant mouse TREML1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TREML1/TLT-1 Antibody [Alexa Fluor® 594]

• dJ238O23.3
• GLTL1825
• PRO3438
• TLT1
• TLT-1
• TLT1MGC119173
• TREML1
• trem-like transcript 1 protein
• triggering receptor expressed on myeloid cells-like 1
• Triggering receptor expressed on myeloid cells-like protein 1

Background

TREML1 is a type I transmembrane protein that differs from TREM in the cytoplasmic region by having two ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif). A splice variant lacking ITIMs in its cytoplasmic domain also exists. TREML1 is found only in platelets and megakaryocytes. The extracellular region of human and mouse TREML1 share 75% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.