Transferrin Antibody

Product Discontinued

Transferrin Antibody Summary

• Immunogen: Full length native protein (purified) (Human).
• Localization: Secreted
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TF
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000 - 1:30000
  • Immunocytochemistry/ Immunofluorescence 1:200-1:2000
  • Immunohistochemistry 1:200-1:2000
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:1000- 1:30000
• Application Notes: ELISA: 1:100 - 1:1000 (coating), 1:1000 - 1:30000 (primary), WB: 1:1000 - 1:10000 (Colorimetric detection), 1:1000 - 1:30000 (Chemiluminescent detection. Predicted molecular weight: 77 kDa.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Transferrin Antibody

• Beta-1 metal-binding globulin
• DKFZp781D0156
• EC 3.4.21
• PRO1557
• PRO2086
• Serotransferrin
• Siderophilin
• TF
• Transferrin

Background

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Transferrin Antibody (NB110-16316)(1)

Publication using NB110-16316

• Brandstatter H, Schulz P, Polunic I et al. Purification and biochemical characterization of functional complement factor H from human plasma fractions. Vox Sang 2012-10-01 [PMID: 22497541]

Bioinformatics

• Gene Symbol: TF
• Entrez:
  • 7018(Human)
• Uniprot:
  • P02787(Human)