Human TRAILR3/TNFRSF10C ELISA Kit (Colorimetric)

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ELISA: Human TRAILR3/TNFRSF10C ELISA Kit (Colorimetric) [NBP3-14638] - Example of Human TRAILR3/TNFRSF10C Standard Curve.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, Cell lysates
Standard Curve Range
312.5-10000 pg/ml
Sensitivity
147 pg/ml

Order Details

Human TRAILR3/TNFRSF10C ELISA Kit (Colorimetric) Summary

Description
Incubation: 3 hours 40 minutes
Specificity
Specific for human TRAILR3/TNFRSF10C. No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R2, TRAIL R4, CD178, and Granzyme B..
Standard Curve Range
312.5-10000 pg/ml
Sensitivity
147 pg/ml
Assay Type
Sandwich ELISA
Inter-Assay
CV% < 9.7
Intra-Assay
CV% < 6.8
Spike Recovery
103 to 122%
Sample Volume
100 ul
Kit Type
ELISA Kit (Colorimetric)
Gene
TNFRSF10C

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.

Kit Components

Components
  1. Biotinylated secondary antibody
  2. Buffers
  3. Controls (where applicable)
  4. Detailed procedure.
  5. Pre-coated strip plates
  6. Standards
  7. Stop reagents
  8. Streptavidin-HRP
  9. TMB

Alternate Names for Human TRAILR3/TNFRSF10C ELISA Kit (Colorimetric)

  • Antagonist decoy receptor for TRAIL/Apo-2L
  • CD263 antigen
  • CD263
  • cytotoxic TRAIL receptor-3
  • DcR1
  • DCR1MGC149502
  • Decoy receptor 1
  • Decoy TRAIL receptor without death domain
  • LITMGC149501
  • Lymphocyte inhibitor of TRAIL
  • TNFRSF10C
  • TRAIL R3
  • TRAIL receptor 3
  • TRAIL receptor without an intracellular domain
  • TRAILR3
  • TRAIL-R3
  • TRAILR3TNF-related apoptosis-inducing ligand receptor 3
  • TRIDDCR1-TNFR
  • tumor necrosis factor receptor superfamily member 10C
  • tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

Background

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF10C