TRAILR3/TNFRSF10C Products

Description

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Bioinformatics

Entrez	8794 Human
Uniprot	AAB67104 Human AF012536 Human NP_003832 Human NP_003832.2 Human O14798 Human
Product By Gene ID	8794
Alternate Names	Antagonist decoy receptor for TRAIL/Apo-2L CD263 antigen CD263 cytotoxic TRAIL receptor-3 DcR1 DCR1MGC149502 Decoy receptor 1 Decoy TRAIL receptor without death domain LITMGC149501 Lymphocyte inhibitor of TRAIL TNFRSF10C TRAIL receptor 3 TRAIL receptor without an intracellular domain TRAIL-R3 TRAILR3TNF-related apoptosis-inducing ligand receptor 3 TRIDDCR1-TNFR tumor necrosis factor receptor superfamily member 10C tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

Research Areas for TRAILR3/TNFRSF10C

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Breast Cancer
Cell Biology
Chromatin Research
Cytokine Research
Immunology
Innate Immunity
Signal Transduction