TRAF3IP2 Antibody [DyLight 488]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 488

TRAF3IP2 Antibody [DyLight 488] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Synthetic peptide corresponding to the N-terminus of human ACT.
• Specificity: Reacts with the N terminus of ACT
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TRAF3IP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-93556. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

This antibody is reactive against Human, Mouse

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TRAF3IP2 Antibody [DyLight 488]

• ACT1DKFZP586G0522
• adapter protein CIKS
• C6orf2
• C6orf4chromosome 6 open reading frame 5
• C6orf5DKFZp586G0522
• C6orf6MGC3581
• CIKSchromosome 6 open reading frame 2
• Connection to IKK and SAPK/JNK
• NFkB-activating protein ACT1
• Nuclear factor NF-kappa-B activator 1
• TRAF3 interacting protein 2
• TRAF3-interacting protein 2

Background

TRAF3IP2 encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRAF3IP2