TPX2 Antibody

Product Discontinued

TPX2 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human TPX2. The exact sequence is proprietary.
• Localization: Nucleus; Spindle
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TPX2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 86 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Expected cross reactivity based on sequence homology: Mouse (86%), Rat (85%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for TPX2 Antibody

• C20orf1HCTP4
• C20orf2
• chromosome 20 open reading frame 1
• Differentially expressed in cancerous and non-cancerous lung cells 2
• differentially expressed in lung cells
• DIL2
• DIL-2FLS353
• HCA519
• Hepatocellular carcinoma-associated antigen 519
• P100
• p100GD:C20orf1
• preferentially expressed in colorectal cancer
• Protein fls353
• REPP86
• restricted expression proliferation associated protein 100
• Restricted expression proliferation-associated protein 100
• targeting protein for Xklp2
• TPX2, microtubule-associated protein homolog
• TPX2, microtubule-associated, homolog (Xenopus laevis)

Background

TPX2 is a microtubule cross-linking protein involved in spindle formation. During mitosis, it is strictly associated with the mitotic spindle, whereas during phases S and G2 it is diffusely distributed throughout the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: TPX2
• Uniprot:
  • Q9ULW0(Human)