TOX3 Antibody (TOX3/1123) [DyLight 594]

• Reactivity: Hu, Ch
• Applications: WB, ELISA, ICC/IF, IHC, MA
• Clone: TOX3/1123
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 594

TOX3 Antibody (TOX3/1123) [DyLight 594] Summary

• Immunogen: Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405)
• Localization: Cytoplasmic & Nuclear
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TOX3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Chicken reactivity reported from a verified customer review.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TOX3 Antibody (TOX3/1123) [DyLight 594]

• CAG trinucleotide repeat-containing gene F9 protein
• CAGF9trinucleotide repeat containing 9
• TNRC9
• TOX high mobility group box family member 3
• Trinucleotide repeat-containing gene 9 protein

Background

The protein encoded by the TOX3 gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TOX3