TNFRH3/TNFRSF26 Antibody [Alexa Fluor® 700]

• Applications: WB, Flow, CyTOF-ready
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 700

TNFRH3/TNFRSF26 Antibody [Alexa Fluor® 700] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse TNFRH3/TNFRSF26
  Ser20-Lys162
  Accession # P83626
• Specificity: Detects mouse TNFRH3/TNFRSF26 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant mouse (rm) TNF RI and rmTNF RII is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

TNFRH3 (Tumor necrosis factor receptor homolog 3; also TNFR superfamily member 26) is a 21 kDa (predicted) member of the TNF receptor superfamily. It appears to be concentrated in lymphoid cell types. Mature mouse TNFRH3 is a type I transmembrane protein that is 185 amino acid (aa) in length. It contains a 145 aa extracellular region and a 19 aa cytoplasmic domain. The extracellular region contains three TNFR-Cys repeats that characterize TNF receptors (aa 27‑143). Unlike two related TNF receptor homologs, TNFRH3 does not serve as a TRAIL decoy receptor. No ortholog to mouse TNFRH3 has been reported in human or rat.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.