TIMP-2 Antibody (MM0035-2C13)


Immunohistochemistry-Paraffin: TIMP2 Antibody (MM0035-2C13) [NB110-61001] - Formalin fixed and paraffin embedded normal human placenta tissue is subjected to mouse anti human TIMP-2

Product Details

Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
LYOPH mg/ml

Order Details

TIMP-2 Antibody (MM0035-2C13) Summary

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2).
TIMP-2. No cross-reactivity to human TIMP-1 is noted.
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
From PBS.
No Preservative
LYOPH mg/ml
Protein G purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.

Reactivity Notes


Alternate Names for TIMP-2 Antibody (MM0035-2C13)

  • CSC-21Ktissue inhibitor of metalloproteinase 2
  • metalloproteinase inhibitor 2
  • TIMP metallopeptidase inhibitor 2
  • TIMP2
  • TIMP-2
  • Tissue inhibitor of metalloproteinases 2


Matrix metalloproteinases (MMPs) are a family of enzymes that are responsible for the degradation of extracellular matrix components such as collagen, laminin and proteoglycans. These enzymes are involved in normal physiological processes such as embryogenesis and tissue remodeling and may play an important role in arthritis, periodontitis, and metastasis. The activation and activity of MMPs are regulated by a family of endogenous inhibitors, tissue inhibitors of metalloproteinase (TIMP). TIMP2 (also called CSC-21K) is a 21 kDa glycoprotein that is expressed by a variety of cell types. It forms a non covalent, stoichiometric complex with both latent and active MMPs. TIMP2 shows a preference for MMP2. TIMPs are capable of altering the metastatic potential of cancer cells and have been shown to inhibit invasion and metastasis in animal models. TIMP2 is constitutively produced in low (pg/ml) levels by most cell types in tissue culture. The low protein levels produced often require concentration of cell culture media to visualize the bands by Western Blotting.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt, Ch, GP
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, IHC
Species: Hu
Applications: WB, Simple Western

Publications for TIMP-2 Antibody (NB110-61001) (0)

There are no publications for TIMP-2 Antibody (NB110-61001).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TIMP-2 Antibody (NB110-61001) (0)

There are no reviews for TIMP-2 Antibody (NB110-61001). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TIMP-2 Antibody (NB110-61001) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Additional TIMP-2 Antibody (MM0035-2C13) Products

Related Products by Gene

Bioinformatics Tool for TIMP-2 Antibody (NB110-61001)

Discover related pathways, diseases and genes to TIMP-2 Antibody (NB110-61001). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TIMP-2 Antibody (NB110-61001)

Discover more about diseases related to TIMP-2 Antibody (NB110-61001).

Pathways for TIMP-2 Antibody (NB110-61001)

View related products by pathway.

PTMs for TIMP-2 Antibody (NB110-61001)

Learn more about PTMs related to TIMP-2 Antibody (NB110-61001).

Research Areas for TIMP-2 Antibody (NB110-61001)

Find related products by research area.

Blogs on TIMP-2

There are no specific blogs for TIMP-2, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol TIMP2

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NB110-61001 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought